What if humans could regrow their teeth? Sounds interesting, doesn’t it? However, it is presumably impossible for teeth to regrow, and a team of scientists has created a drug to regrow teeth. The process of growing teeth back could be just around the corner, it is said, as a team of Japanese pharmaceutical startups are set to begin human trials of a new drug that has managed to grow new teeth in animals. . Recently, The Japan Times reported that Toregem Biopharma would begin clinical trials in July next year after successfully growing new teeth in mice five years ago. If you find this development interesting and think it would be a great achievement in medical science, stay on this page and continue reading this article until the end.
Human trials of new drug to grow back missing teeth to begin soon
Dr. Katsu Takahashi, head of the department of dentistry and oral surgery at Kitano Hospital of the Medical Research Institute, is one of the principal investigators of this project. Dr. Takahashi recently said, “The thought of having new teeth is every dentist’s dream.” “I’ve been working on this since I was a graduate student.” Earlier this year, Dr. Katsu told the Mainichi: “I was sure he could do it.” Take a look below and read more details.
Research on the new drug is reportedly currently underway at Kyoto University. Note that this research has been going on since 2005. Five years ago, during research, researchers saw teeth growing back in mice when they learned about a particular gene. The antibody for this particular gene is called USAG-1. It can accelerate tooth growth if suppressed. Since then, the Japanese medical team has been working hard to create a “neutralizing antibody drug” that is capable of blocking USAG-1.
Now Dr. Katsu’s team and his team are working on the theory of blocking the antibody to this USAG-1 gene that can grow more unwanted teeth. However, they have been shown to be successful in mice and ferrets, animals that have similar tooth structure to humans. Now, researchers are ready to begin human trials. If all goes well, doctors will conduct clinical trials with children ages 2 to 6 who suffer from anodontia, a rare genetic disorder that causes six or more missing teeth.
Categories: Biography
Source: vtt.edu.vn